As with other antipsychotics, may develop anavar neuroleptic malignant syndrome, characterized by hyperthermia, muscle rigidity, dysfunction of the peripheral nervous system, elevated levels of creatinine phosphokinase. With the development of hyperthermia, especially during treatment with high doses, all antipsychotic drugs including Amisulpride should be repealed.
Withdrawal amisulpride carried kidneys. In the case of serious violations of renal function should be used to reduce the dose and regimen described in the section “Dosage and method of administration.”
Since there is no experience with the drug in patients with severe renal impairment (CRCL !! 10 mL / min), in their case, special care is required.
Since the drug is weakly metabolized in hepatic dysfunction dose reduction is required.
Amisulpride may lower the seizure threshold. Therefore, patients with epilepsy in history require constant monitoring during therapy amisulpride.
In old age, Amisulpride, like other neuroleptics, should be used with special caution because of a possible risk of hypotension or excessive sedation.
In Parkinson’s disease, the appointment antidofaminergicheskih drugs and amisulpride , care should be taken because of the possible deterioration.
Amisulpride should be used only if neuroleptic treatment can not be avoided.
prolongation of the QT interval:
Amisulpride causes a dose-dependent prolongation of the anavar interval. It is known that this effect increases the risk of serious ventricular arrhythmias, and it is amplified in the presence of bradycardia, hypokalemia, congenital or acquired QT interval prolongation.
Before prescribing the drug, and, if possible, depending on the clinical status of the patient, it is recommended to monitor factors which may contribute to the development of cardiac arrhythmias:

  • Bradycardia below 55 beats / min
  • hypokalemia,
  • Congenital prolongation of the interval
  • Concomitant use of drugs that can cause severe bradycardia (<55 bpm. / Min), hypokalemia, conductivity reduction or prolongation of the interval (see. Section “Interactions with other medicinal products”).

Effects on ability to drive and perform work requiring special attention

Amisulpride affect the reaction rate, resulting in ability to drive or operate machinery may be impaired.

Safety Amisulpride has anavar not been established during pregnancy. Therefore, the use of the drug during pregnancy is not recommended, except in cases where the benefit justifies the potential risk. how much to inject for weight loss

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